close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBCobyrinic acid ACdiamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (436 aa)    
Predicted Functional Partners:
BF49_1433
Cobaltprecorrin8x methylmutase EC 5412.
 
 
 0.999
BF49_1435
CobN component of cobalt chelatase involved in B12 biosynthesis.
 
 
 0.998
BF49_0603
Aerobic cobaltochelatase CobS subunit EC 6612.
     
 0.990
BF49_1427
Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family.
 
 
 0.980
BF49_1429
Precorrin-6Y C5,15-methyltransferase (decarboxylating); Cobaltprecorrin6y C5methyltransferase EC 211 Cobaltprecorrin6y C15methyltransferase decarboxylating EC 211.
 
  
 0.980
BF49_1438
CobIalamin adenosyltransferase EC 25117; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.979
cobT
Nicotinatenucleotidedimethylbenzimidazole phosphoribosyltransferase EC 24221; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
  
 0.972
cobQ
Cobyric acid synthase EC 63510; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.968
BF49_1428
Cobalamin biosynthesis protein CobE.
 
  
 0.963
BF49_0606
Aerobic cobaltochelatase CobT subunit EC 6612.
     
  0.959
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: low (20%) [HD]