| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_1423 | BF49_1427 | BF49_1423 | BF49_1427 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | 0.999 |
| BF49_1423 | BF49_1428 | BF49_1423 | BF49_1428 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobalamin biosynthesis protein CobE. | 0.985 |
| BF49_1423 | BF49_1429 | BF49_1423 | BF49_1429 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Precorrin-6Y C5,15-methyltransferase (decarboxylating); Cobaltprecorrin6y C5methyltransferase EC 211 Cobaltprecorrin6y C15methyltransferase decarboxylating EC 211. | 0.992 |
| BF49_1423 | BF49_1430 | BF49_1423 | BF49_1430 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobaltprecorrin6x reductase EC 13154. | 0.999 |
| BF49_1423 | BF49_1431 | BF49_1423 | BF49_1431 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobaltprecorrin3b C17methyltransferase. | 0.980 |
| BF49_1423 | BF49_1432 | BF49_1423 | BF49_1432 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobaltprecorrin2 C20methyltransferase EC 211130; Belongs to the precorrin methyltransferase family. | 0.868 |
| BF49_1423 | BF49_1433 | BF49_1423 | BF49_1433 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobaltprecorrin8x methylmutase EC 5412. | 0.983 |
| BF49_1423 | BF49_1435 | BF49_1423 | BF49_1435 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | CobN component of cobalt chelatase involved in B12 biosynthesis. | 0.855 |
| BF49_1423 | BF49_4254 | BF49_1423 | BF49_4254 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.796 |
| BF49_1423 | cobB | BF49_1423 | BF49_1426 | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | Cobyrinic acid ACdiamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.894 |
| BF49_1427 | BF49_1423 | BF49_1427 | BF49_1423 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Precorrin6A synthase EC 211152; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.999 |
| BF49_1427 | BF49_1428 | BF49_1427 | BF49_1428 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobE. | 0.999 |
| BF49_1427 | BF49_1429 | BF49_1427 | BF49_1429 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Precorrin-6Y C5,15-methyltransferase (decarboxylating); Cobaltprecorrin6y C5methyltransferase EC 211 Cobaltprecorrin6y C15methyltransferase decarboxylating EC 211. | 0.998 |
| BF49_1427 | BF49_1430 | BF49_1427 | BF49_1430 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Cobaltprecorrin6x reductase EC 13154. | 0.995 |
| BF49_1427 | BF49_1431 | BF49_1427 | BF49_1431 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Cobaltprecorrin3b C17methyltransferase. | 0.999 |
| BF49_1427 | BF49_1432 | BF49_1427 | BF49_1432 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Cobaltprecorrin2 C20methyltransferase EC 211130; Belongs to the precorrin methyltransferase family. | 0.990 |
| BF49_1427 | BF49_1433 | BF49_1427 | BF49_1433 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Cobaltprecorrin8x methylmutase EC 5412. | 0.988 |
| BF49_1427 | BF49_1435 | BF49_1427 | BF49_1435 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | CobN component of cobalt chelatase involved in B12 biosynthesis. | 0.857 |
| BF49_1427 | BF49_4254 | BF49_1427 | BF49_4254 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.897 |
| BF49_1427 | cobB | BF49_1427 | BF49_1426 | Cobaltprecorrin4 C11methyltransferase EC 211133; Belongs to the precorrin methyltransferase family. | Cobyrinic acid ACdiamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.988 |