Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (260 aa)    
Predicted Functional Partners:
BF49_1442
Adenosylcobinamidephosphate guanylyltransferase EC 27762; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
 
 
 0.999
cobT
Nicotinatenucleotidedimethylbenzimidazole phosphoribosyltransferase EC 24221; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.994
BF49_1421
Alpharibazole5phosphate phosphatase EC 31373.
 
 
 0.987
BF49_1438
CobIalamin adenosyltransferase EC 25117; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.986
BF49_6189
Hypothetical protein bll5443.
 
 
 0.978
cobQ
Cobyric acid synthase EC 63510; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.960
BF49_1431
Cobaltprecorrin3b C17methyltransferase.
 
  
 0.949
BF49_1444
Cobalamin biosynthesis protein BluB 56dimethylbenzimidazole synthase flavin destructase family.
 
 
 0.940
cobD
Adenosylcobinamidephosphate synthase EC 63110; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.936
BF49_3287
ATPCobIalamin adenosyltransferase EC 25117; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.934
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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