Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
BF49_1555Response regulator in twocomponent regulatory system with PhoQ. (226 aa)    
Predicted Functional Partners:
BF49_1554
Sensor protein basSpmrB EC 273.
 
 0.970
BF49_2142
Twocomponent hybrid sensor and regulator.
  
 0.905
BF49_2815
Sensor histidine kinase.
 0.882
BF49_3244
Chemotaxis protein methyltransferase CheR EC 21180.
 
 0.881
BF49_1446
Sensory box histidine kinaseresponse regulator.
 
 0.876
BF49_0183
Twocomponent hybrid sensor and regulator.
 
 0.850
BF49_6780
Sensor histidine kinase with PASPAC and response regulator receiver domains EC 273.
 
 0.838
glnE
Glutamateammonialigase adenylyltransferase EC 27742; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal [...]
     
 0.817
BF49_1860
Sensory box histidine kinaseresponse regulator.
 
 0.817
BF49_4934
Chemotaxis regulator transmits chemoreceptor signals to flagelllar motor components CheY.
 
 0.815
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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