Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_1580Acetolactate synthase large subunit EC 2216; Belongs to the TPP enzyme family. (544 aa)    
Predicted Functional Partners:
BF49_5173
Acetolactate synthase small subunit EC 2216.
 
 0.951
BF49_1727
Acetolactate synthase large subunit EC 2216; Belongs to the TPP enzyme family.
  
  
 
0.926
BF49_5171
Acetolactate synthase large subunit EC 2216.
  
  
 
0.924
BF49_1515
Glyoxylate carboligase EC 41147; Belongs to the TPP enzyme family.
  
  
 
0.921
BF49_1045
Acetolactate synthase large subunit EC 2216; Belongs to the TPP enzyme family.
  
  
 
0.918
BF49_4844
Acetolactate synthase large subunit EC 2216; Belongs to the TPP enzyme family.
  
  
 
0.917
ilvC
Ketolacid reductoisomerase EC 11186; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.917
ilvD
Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family.
 
 
 0.816
ilvD-2
Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family.
 
 
 0.797
BF49_1857
Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family.
 
 
 0.737
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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