| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0091 | BF49_1631 | BF49_0091 | BF49_1631 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| BF49_0091 | BF49_1632 | BF49_0091 | BF49_1632 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.862 |
| BF49_0091 | BF49_1633 | BF49_0091 | BF49_1633 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 2amino4hydroxy6 hydroxymethyldihydropteridine pyrophosphokinase EC 2763. | 0.899 |
| BF49_0091 | BF49_2112 | BF49_0091 | BF49_2112 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 34dihydroxy2butanone 4phosphate synthase EC 419912 GTP cyclohydrolase II EC 35425; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.786 |
| BF49_0091 | BF49_2303 | BF49_0091 | BF49_2303 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | Anthranilate synthase aminase component EC 41327 Anthranilate synthase amidotransferase component EC 41327. | 0.741 |
| BF49_0091 | folE | BF49_0091 | BF49_1709 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I EC 35416 type 1. | 0.673 |
| BF49_0091 | folE-2 | BF49_0091 | BF49_6119 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I EC 35416 type 1. | 0.673 |
| BF49_0091 | mltG | BF49_0091 | BF49_0980 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | FIG004453 protein YceG like; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.624 |
| BF49_1631 | BF49_0091 | BF49_1631 | BF49_0091 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 0.999 |
| BF49_1631 | BF49_1632 | BF49_1631 | BF49_1632 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| BF49_1631 | BF49_1633 | BF49_1631 | BF49_1633 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2amino4hydroxy6 hydroxymethyldihydropteridine pyrophosphokinase EC 2763. | 0.999 |
| BF49_1631 | BF49_2112 | BF49_1631 | BF49_2112 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 34dihydroxy2butanone 4phosphate synthase EC 419912 GTP cyclohydrolase II EC 35425; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.767 |
| BF49_1631 | BF49_2303 | BF49_1631 | BF49_2303 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase aminase component EC 41327 Anthranilate synthase amidotransferase component EC 41327. | 0.959 |
| BF49_1631 | BF49_5957 | BF49_1631 | BF49_5957 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Metaldependent hydrolases of the betalactamase superfamily II. | 0.900 |
| BF49_1631 | folE | BF49_1631 | BF49_1709 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I EC 35416 type 1. | 0.974 |
| BF49_1631 | folE-2 | BF49_1631 | BF49_6119 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I EC 35416 type 1. | 0.975 |
| BF49_1631 | mltG | BF49_1631 | BF49_0980 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | FIG004453 protein YceG like; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.790 |
| BF49_1631 | ribH-2 | BF49_1631 | BF49_6548 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 67dimethyl8ribityllumazine synthase EC 25178; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.826 |
| BF49_1632 | BF49_0091 | BF49_1632 | BF49_0091 | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 0.862 |
| BF49_1632 | BF49_1631 | BF49_1632 | BF49_1631 | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |