| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0091 | BF49_1631 | BF49_0091 | BF49_1631 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| BF49_0091 | BF49_1632 | BF49_0091 | BF49_1632 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.851 |
| BF49_0091 | BF49_1633 | BF49_0091 | BF49_1633 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 2amino4hydroxy6 hydroxymethyldihydropteridine pyrophosphokinase EC 2763. | 0.854 |
| BF49_0091 | BF49_2112 | BF49_0091 | BF49_2112 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 34dihydroxy2butanone 4phosphate synthase EC 419912 GTP cyclohydrolase II EC 35425; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.719 |
| BF49_0091 | BF49_2303 | BF49_0091 | BF49_2303 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | Anthranilate synthase aminase component EC 41327 Anthranilate synthase amidotransferase component EC 41327. | 0.672 |
| BF49_0091 | BF49_6546 | BF49_0091 | BF49_6546 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.761 |
| BF49_0091 | folE | BF49_0091 | BF49_1709 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I EC 35416 type 1. | 0.654 |
| BF49_0091 | folE-2 | BF49_0091 | BF49_6119 | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I EC 35416 type 1. | 0.654 |
| BF49_1631 | BF49_0091 | BF49_1631 | BF49_0091 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 0.999 |
| BF49_1631 | BF49_1632 | BF49_1631 | BF49_1632 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| BF49_1631 | BF49_1633 | BF49_1631 | BF49_1633 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2amino4hydroxy6 hydroxymethyldihydropteridine pyrophosphokinase EC 2763. | 0.999 |
| BF49_1631 | BF49_2112 | BF49_1631 | BF49_2112 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 34dihydroxy2butanone 4phosphate synthase EC 419912 GTP cyclohydrolase II EC 35425; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.739 |
| BF49_1631 | BF49_2303 | BF49_1631 | BF49_2303 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase aminase component EC 41327 Anthranilate synthase amidotransferase component EC 41327. | 0.931 |
| BF49_1631 | BF49_5957 | BF49_1631 | BF49_5957 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Metaldependent hydrolases of the betalactamase superfamily II. | 0.918 |
| BF49_1631 | BF49_6546 | BF49_1631 | BF49_6546 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.708 |
| BF49_1631 | folE | BF49_1631 | BF49_1709 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I EC 35416 type 1. | 0.969 |
| BF49_1631 | folE-2 | BF49_1631 | BF49_6119 | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I EC 35416 type 1. | 0.971 |
| BF49_1632 | BF49_0091 | BF49_1632 | BF49_0091 | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family. | 0.851 |
| BF49_1632 | BF49_1631 | BF49_1632 | BF49_1631 | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| BF49_1632 | BF49_1633 | BF49_1632 | BF49_1633 | Dihydroneopterin aldolase EC 41225; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2amino4hydroxy6 hydroxymethyldihydropteridine pyrophosphokinase EC 2763. | 0.999 |