STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_1728FIG01008325 hypothetical protein. (413 aa)    
Predicted Functional Partners:
BF49_1729
Alkylated DNA repair protein AlkB.
       0.624
BF49_1730
FIG00443816 hypothetical protein.
       0.598
BF49_6582
PROBABLE TRANSMEMBRANE PROTEIN.
  
    0.512
BF49_0605
Hypothetical protein.
  
     0.479
BF49_4301
NADPHdependent glyceraldehyde3phosphate dehydrogenase EC 12113 NADdependent glyceraldehyde3phosphate dehydrogenase EC 12112; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.459
thyA
Thymidylate synthase EC 21145; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.420
ndk
Nucleoside diphosphate kinase EC 2746; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.418
BF49_1731
FIG01006931 hypothetical protein.
       0.400
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.