Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ppcPhosphoenolpyruvate carboxylase EC 41131; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (929 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase EC 11137; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.992
BF49_6722
Citrate synthase si EC 2331; Belongs to the citrate synthase family.
     
 0.980
eno
Enolase EC 42111; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.966
BF49_2250
Pyruvatephosphate dikinase EC 2791.
     
 0.963
BF49_4394
Pyruvate kinase EC 27140; Belongs to the pyruvate kinase family.
     
 0.957
BF49_0597
Citrate synthase si EC 2331; Belongs to the citrate synthase family.
     
 0.944
BF49_0598
Citrate synthase si EC 2331.
     
 0.939
pckA
Phosphoenolpyruvate carboxykinase ATP EC 41149; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.935
BF49_6364
Bll5266 protein; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
    
 0.913
BF49_3171
Glutamate synthase NADPH large chain EC 14113.
  
  
 0.906
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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