Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_1808FIG00444077 hypothetical protein. (127 aa)    
Predicted Functional Partners:
BF49_6759
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.965
BF49_0406
2oxoglutarate dehydrogenase E1 component EC 1242.
  
 0.964
BF49_1868
Pyruvate dehydrogenase E1 component EC 1241; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.925
sucC
SuccinylCoA ligase ADPforming beta chain EC 6215; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.908
pdhA
Pyruvate dehydrogenase E1 component alpha subunit EC 1241; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.908
BF49_0410
Dihydrolipoamide dehydrogenase of 2oxoglutarate dehydrogenase EC 1814.
  
 0.891
BF49_1287
Glutathione reductase EC 1817; Maintains high levels of reduced glutathione.
  
 0.891
BF49_1914
Similar to glutathione reductase.
  
 0.891
BF49_6764
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex EC 1814.
  
 0.891
sucD
SuccinylCoA ligase ADPforming alpha chain EC 6215; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.854
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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