Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BF49_1816FIG00852950 hypothetical protein. (85 aa)    
Predicted Functional Partners:
BF49_1815
FIG00443026 hypothetical protein.
       0.785
BF49_0486
LysM domain protein.
  
    0.758
BF49_1814
Hypothetical protein.
       0.638
BF49_1813
Epoxide hydrolase.
       0.635
BF49_6387
Multimeric flavodoxin WrbA.
  
    0.615
BF49_3096
Flavoprotein WrbA.
   
    0.565
BF49_6468
Multimeric flavodoxin WrbA.
   
    0.565
BF49_5806
Flagellar transacting factor FliX.
  
     0.546
parC
Topoisomerase IV subunit A EC 5991; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
  
    0.534
gyrA
DNA gyrase subunit A EC 59913; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.534
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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