Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BF49_1914Similar to glutathione reductase. (453 aa)    
Predicted Functional Partners:
BF49_6759
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.995
BF49_0913
Glutathione peroxidase family protein; Belongs to the glutathione peroxidase family.
  
 0.961
BF49_4920
Glutathione peroxidase family protein; Belongs to the glutathione peroxidase family.
  
 0.961
BF49_0408
Dihydrolipoamide succinyltransferase component E2 of 2oxoglutarate dehydrogenase complex EC 23161; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.959
BF49_6762
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.959
BF49_3346
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
    
 0.947
gshB
Glutathione synthetase EC 6323; Belongs to the prokaryotic GSH synthase family.
     
 0.935
BF49_1287
Glutathione reductase EC 1817; Maintains high levels of reduced glutathione.
  
  
 
0.921
BF49_0406
2oxoglutarate dehydrogenase E1 component EC 1242.
  
 0.917
BF49_0074
Gammaglutamyltranspeptidase EC 2322.
     
 0.907
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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