Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_2115Valinepyruvate aminotransferase EC 26166. (409 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase decarboxylating glycine cleavage system P protein EC 1442; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.926
glyA
Serine hydroxymethyltransferase EC 2121; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.909
BF49_0473
Serineglyoxylate aminotransferase EC 26145.
  
 
 0.908
BF49_5632
Serineglyoxylate aminotransferase EC 26145.
  
 
 0.908
BF49_5886
Aminomethyltransferase glycine cleavage system T protein EC 21210.
  
 
 0.908
BF49_0889
Glutamine synthetase type II eukaryotic EC 6312.
    
 0.906
BF49_6608
Glutamine synthetase type I EC 6312.
    
 0.906
BF49_0069
Glyoxylate reductase EC 11179 Glyoxylate reductase EC 11126 Hydroxypyruvate reductase EC 11181; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.905
BF49_1500
Alanine dehydrogenase EC 1411; Belongs to the AlaDH/PNT family.
    
 0.904
BF49_4361
D3phosphoglycerate dehydrogenase EC 11195.
    
  0.902
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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