Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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BF49_2216TsaC protein YrdCSua5 domains required for threonylcarbamoyladenosine t6A37 modification in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (329 aa)    
Predicted Functional Partners:
tsaD
TsaDKae1Qri7 protein required for threonylcarbamoyladenosine t6A37 formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 0.947
BF49_0083
N-acetylmuramate 1-kinase; TsaE protein required for threonylcarbamoyladenosine t6A37 formation in tRNA Phosphotransferase involved in threonylcarbamoyladenosine t6A37 formation in tRNA.
    
 0.883
BF49_2218
GCN5related Nacetyltransferase.
    
 0.871
glyA
Serine hydroxymethyltransferase EC 2121; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.796
BF49_2219
Nudix hydrolase family protein YffH.
       0.749
BF49_2217
D2hydroxyglutarate dehydrogenase.
       0.743
prmC
ProteinN5glutamine methyltransferase PrmC methylates polypeptide chain release factors RF1 and RF2; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
  
 0.706
BF49_0027
TsaB protein required for threonylcarbamoyladenosine t6A formation in tRNA.
    
 0.666
BF49_7352
TsaB protein required for threonylcarbamoyladenosine t6A formation in tRNA.
    
 0.666
rpoZ
DNAdirected RNA polymerase omega subunit EC 2776; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.572
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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