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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_2232Folatedependent protein for FeS cluster synthesisrepair in oxidative stress; Belongs to the GcvT family. (283 aa)    
Predicted Functional Partners:
BF49_2233
DNA3methyladenine glycosylase EC 32220.
       0.801
BF49_2234
COG1896 Predicted hydrolases of HD superfamily.
  
    0.744
gcvP
Glycine dehydrogenase decarboxylating glycine cleavage system P protein EC 1442; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.694
BF49_6783
Probable iron binding protein from the HesB IscA SufA family; Belongs to the HesB/IscA family.
 
 
 0.635
BF49_0715
Iron binding protein SufA for ironsulfur cluster assembly; Belongs to the HesB/IscA family.
 
 
 0.596
BF49_5163
Dihydrofolate reductase EC 1513; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
   
 
 0.589
BF49_2231
Dihydroorotase EC 3523.
       0.578
glyA
Serine hydroxymethyltransferase EC 2121; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.564
BF49_5886
Aminomethyltransferase glycine cleavage system T protein EC 21210.
     
 0.563
BF49_5941
FIG00446651 hypothetical protein.
  
  
  0.552
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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