STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_2296Methyltransferase EC 211. (325 aa)    
Predicted Functional Partners:
rsmA
SSU rRNA adenine1518N6adenine1519N6 dimethyltransferase EC 211182; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 
 0.762
rpsP
SSU ribosomal protein S16p; Belongs to the bacterial ribosomal protein bS16 family.
   
 
 0.732
rpsE
SSU ribosomal protein S5p S2e; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
 
 0.722
rpsJ
SSU ribosomal protein S10p S20e; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
 
 0.719
rpsI
SSU ribosomal protein S9p S16e; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.709
rpsF
SSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA.
    
   0.706
rpsG
SSU ribosomal protein S7p S5e; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
    
   0.706
rpsB
SSU ribosomal protein S2p SAe; Belongs to the universal ribosomal protein uS2 family.
   
   0.703
rpsL
SSU ribosomal protein S12p S23e; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
   0.700
rpsQ
SSU ribosomal protein S17p S11e; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.695
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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