Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
aptAdenine phosphoribosyltransferase EC 2427; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa)    
Predicted Functional Partners:
ade
Adenine deaminase EC 3542; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.974
purH
IMP cyclohydrolase EC 35410 Phosphoribosylaminoimidazolecarboxamide formyltransferase EC 2123.
  
 0.973
BF49_5952
Adenylosuccinate lyase EC 4322; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.967
mtnP
5methylthioadenosine phosphorylase EC 24228; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
 
 0.965
adk
Adenylate kinase EC 2743 histone protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.958
amn
AMP nucleosidase EC 3224; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
   
 0.950
surE
5nucleotidase SurE EC 3135; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.930
BF49_0169
Nucleoside 5triphosphatase RdgB dHAPTP dITP XTPspecific EC 36115; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 0.924
BF49_2980
COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.918
BF49_2072
5nucleotidase EC 3135; Belongs to the 5'-nucleotidase family.
    
 0.917
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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