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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_2303Anthranilate synthase aminase component EC 41327 Anthranilate synthase amidotransferase component EC 41327. (707 aa)    
Predicted Functional Partners:
trpC
Indole3glycerol phosphate synthase EC 41148; Belongs to the TrpC family.
 0.999
trpD
Anthranilate phosphoribosyltransferase EC 24218; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.999
aroC
Chorismate synthase EC 4235; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 0.991
trpF
Phosphoribosylanthranilate isomerase EC 53124; Belongs to the TrpF family.
 
 0.983
trpB
Tryptophan synthase beta chain EC 42120; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 
 0.977
trpA
Tryptophan synthase alpha chain EC 42120; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.971
BF49_1631
Dihydropteroate synthase EC 25115; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 
 0.931
apt
Adenine phosphoribosyltransferase EC 2427; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.873
BF49_1633
2amino4hydroxy6 hydroxymethyldihydropteridine pyrophosphokinase EC 2763.
 
  
 0.865
BF49_0550
Branchedchain amino acid aminotransferase EC 26142.
 
 
 0.830
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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