| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0208 | BF49_4445 | BF49_0208 | BF49_4445 | Protoporphyrinogen IX oxidase novel form HemJ EC 13. | Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.933 |
| BF49_0208 | hemE | BF49_0208 | BF49_2403 | Protoporphyrinogen IX oxidase novel form HemJ EC 13. | Uroporphyrinogen III decarboxylase EC 41137; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.602 |
| BF49_0208 | hemF | BF49_0208 | BF49_2311 | Protoporphyrinogen IX oxidase novel form HemJ EC 13. | Coproporphyrinogen III oxidase aerobic EC 1333; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.995 |
| BF49_0208 | hemH | BF49_0208 | BF49_3180 | Protoporphyrinogen IX oxidase novel form HemJ EC 13. | Ferrochelatase protoheme ferrolyase EC 49911; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.994 |
| BF49_2310 | BF49_2312 | BF49_2310 | BF49_2312 | 6carboxytetrahydropterin synthase EC 41250 Queuosine biosynthesis QueD PTPSI. | Putative FMN hydrolase EC 313 5Amino65phosphoribitylaminouracil phosphatase. | 0.690 |
| BF49_2310 | hemF | BF49_2310 | BF49_2311 | 6carboxytetrahydropterin synthase EC 41250 Queuosine biosynthesis QueD PTPSI. | Coproporphyrinogen III oxidase aerobic EC 1333; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.717 |
| BF49_2310 | queE | BF49_2310 | BF49_2309 | 6carboxytetrahydropterin synthase EC 41250 Queuosine biosynthesis QueD PTPSI. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
| BF49_2310 | trmL | BF49_2310 | BF49_2308 | 6carboxytetrahydropterin synthase EC 41250 Queuosine biosynthesis QueD PTPSI. | tRNA cytidine342Omethyltransferase EC 211207; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.711 |
| BF49_2312 | BF49_2310 | BF49_2312 | BF49_2310 | Putative FMN hydrolase EC 313 5Amino65phosphoribitylaminouracil phosphatase. | 6carboxytetrahydropterin synthase EC 41250 Queuosine biosynthesis QueD PTPSI. | 0.690 |
| BF49_2312 | hemF | BF49_2312 | BF49_2311 | Putative FMN hydrolase EC 313 5Amino65phosphoribitylaminouracil phosphatase. | Coproporphyrinogen III oxidase aerobic EC 1333; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.798 |
| BF49_2312 | queE | BF49_2312 | BF49_2309 | Putative FMN hydrolase EC 313 5Amino65phosphoribitylaminouracil phosphatase. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.704 |
| BF49_2312 | trmL | BF49_2312 | BF49_2308 | Putative FMN hydrolase EC 313 5Amino65phosphoribitylaminouracil phosphatase. | tRNA cytidine342Omethyltransferase EC 211207; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.608 |
| BF49_2491 | BF49_4445 | BF49_2491 | BF49_4445 | TPR domain protein putative component of TonB system. | Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.440 |
| BF49_2491 | hemF | BF49_2491 | BF49_2311 | TPR domain protein putative component of TonB system. | Coproporphyrinogen III oxidase aerobic EC 1333; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.628 |
| BF49_2491 | hemH | BF49_2491 | BF49_3180 | TPR domain protein putative component of TonB system. | Ferrochelatase protoheme ferrolyase EC 49911; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.594 |
| BF49_4445 | BF49_0208 | BF49_4445 | BF49_0208 | Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Protoporphyrinogen IX oxidase novel form HemJ EC 13. | 0.933 |
| BF49_4445 | BF49_2491 | BF49_4445 | BF49_2491 | Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | TPR domain protein putative component of TonB system. | 0.440 |
| BF49_4445 | hemE | BF49_4445 | BF49_2403 | Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Uroporphyrinogen III decarboxylase EC 41137; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.996 |
| BF49_4445 | hemF | BF49_4445 | BF49_2311 | Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Coproporphyrinogen III oxidase aerobic EC 1333; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.941 |
| BF49_4445 | hemH | BF49_4445 | BF49_3180 | Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ferrochelatase protoheme ferrolyase EC 49911; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.539 |