STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_2345Isocitrate lyase EC 4131. (543 aa)    
Predicted Functional Partners:
glcB
Malate synthase G EC 2339; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
 
 0.999
BF49_0391
Aconitate hydratase EC 4213; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.992
BF49_3546
Phosphate acetyltransferase EC 2318.
   
 
 0.950
BF49_5246
Phosphate acetyltransferase EC 2318.
   
 
 0.950
BF49_3073
Glycolate dehydrogenase EC 119914 ironsulfur subunit GlcF.
     
 0.935
sucC
SuccinylCoA ligase ADPforming beta chain EC 6215; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.934
sucD
SuccinylCoA ligase ADPforming alpha chain EC 6215; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
 0.925
BF49_5632
Serineglyoxylate aminotransferase EC 26145.
    
 0.922
BF49_1515
Glyoxylate carboligase EC 41147; Belongs to the TPP enzyme family.
     
 0.917
BF49_4361
D3phosphoglycerate dehydrogenase EC 11195.
   
 
 0.916
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.