Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_2663Adenylate cyclase EC 4611 Guanylate cyclase EC 4612. (394 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase EC 2746; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.902
BF49_6511
GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
BF49_7015
Nucleoside triphosphate pyrophosphohydrolase MazG EC 3618.
     
  0.900
BF49_2662
Adenylate cyclase EC 4611.
 
     0.808
BF49_2112
34dihydroxy2butanone 4phosphate synthase EC 419912 GTP cyclohydrolase II EC 35425; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
    
  0.803
moaA
Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
 
  0.801
BF49_3089
Adenylate cyclase EC 4611.
  
     0.766
BF49_3754
Adenylate cyclase EC 4611.
  
     0.715
BF49_3206
FIG00443480 hypothetical protein.
  
     0.691
BF49_2800
CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; cAMPbinding proteins catabolite gene activator and regulatory subunit of cAMPdependent protein kinases.
 
   0.681
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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