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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_2793Proline dehydrogenase EC 15998 Proline oxidase Delta1pyrroline5carboxylate dehydrogenase EC 15112; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1003 aa)    
Predicted Functional Partners:
BF49_1681
Acetylornithine aminotransferase EC 26111; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.975
proC
Pyrroline5carboxylate reductase EC 1512; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.958
proB
Glutamate 5kinase EC 27211 RNAbinding Cterminal domain PUA; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
 0.948
BF49_4032
Naproline symporter Sensor histidine kinase PrlS.
  
  
 0.947
proA
Gammaglutamyl phosphate reductase EC 12141; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.946
BF49_3171
Glutamate synthase NADPH large chain EC 14113.
  
 
 0.944
pxpA
Lactam utilization protein LamB; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
   
 
  0.944
BF49_6608
Glutamine synthetase type I EC 6312.
  
 
 0.943
BF49_7160
Putative Cytochrome bd2 subunit I.
   
 
 0.937
BF49_0889
Glutamine synthetase type II eukaryotic EC 6312.
   
 
 0.936
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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