Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_2830Biotin carboxylase EC 63414. (1101 aa)    
Predicted Functional Partners:
BF49_6363
Biotin carboxylase EC 63414 Biotin carboxyl carrier protein.
 
0.959
BF49_7199
MethylcrotonylCoA carboxylase biotincontaining subunit EC 6414.
 
0.959
BF49_3681
MethylcrotonylCoA carboxylase biotincontaining subunit EC 6414.
 
0.958
BF49_7095
MethylcrotonylCoA carboxylase biotincontaining subunit EC 6414.
 
0.958
BF49_3171
Glutamate synthase NADPH large chain EC 14113.
  
 
 0.951
mdh
Malate dehydrogenase EC 11137; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.932
BF49_6759
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.917
accD
Acetylcoenzyme A carboxyl transferase beta chain EC 6412; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
 
 
 0.908
BF49_2674
Conserved hypothetical protein.
 
 
 0.905
BF49_0754
Biotin carboxyl carrier protein of acetylCoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.893
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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