Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BF49_2901MalylCoA lyase EC 41324; Belongs to the HpcH/HpaI aldolase family. (307 aa)    
Predicted Functional Partners:
BF49_2777
COGs COG3777.
  
 
 0.976
BF49_6363
Biotin carboxylase EC 63414 Biotin carboxyl carrier protein.
 
 
 0.940
accA
Acetylcoenzyme A carboxyl transferase alpha chain EC 6412; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
    
 0.931
BF49_0069
Glyoxylate reductase EC 11179 Glyoxylate reductase EC 11126 Hydroxypyruvate reductase EC 11181; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.928
accD
Acetylcoenzyme A carboxyl transferase beta chain EC 6412; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
     
 0.926
BF49_6277
PropionylCoA carboxylase beta chain EC 6413.
  
 
 0.925
BF49_0754
Biotin carboxyl carrier protein of acetylCoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.919
acsA
Acetylcoenzyme A synthetase EC 6211; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.915
BF49_1094
Acetylcoenzyme A synthetase EC 6211.
    
 0.915
BF49_2879
Acetylcoenzyme A synthetase EC 6211.
    
 0.915
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.