Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proCPyrroline5carboxylate reductase EC 1512; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (278 aa)    
Predicted Functional Partners:
BF49_2793
Proline dehydrogenase EC 15998 Proline oxidase Delta1pyrroline5carboxylate dehydrogenase EC 15112; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.966
BF49_4913
Proline iminopeptidase EC 34115; Belongs to the peptidase S33 family.
    
 0.904
proB
Glutamate 5kinase EC 27211 RNAbinding Cterminal domain PUA; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.861
proA
Gammaglutamyl phosphate reductase EC 12141; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.854
argD
Acetylornithine aminotransferase EC 26111; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.775
argB
Acetylglutamate kinase EC 2728; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
   
 0.717
BF49_2987
FIG00449860 hypothetical protein.
 
     0.648
BF49_6187
Acetylornithine deacetylase EC 35116.
  
  
 0.606
BF49_3171
Glutamate synthase NADPH large chain EC 14113.
     
 0.601
rplF
LSU ribosomal protein L6p L9e; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.586
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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