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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiA4hydroxybenzoate polyprenyltransferase EC 25139; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (339 aa)    
Predicted Functional Partners:
BF49_2260
Octaprenyl diphosphate synthase EC 25190 Dimethylallyltransferase EC 2511 2E6Efarnesyl diphosphate synthase EC 25110 Geranylgeranyl pyrophosphate synthetase EC 25129; Belongs to the FPP/GGPP synthase family.
 
 
 0.952
BF49_4142
4hydroxybenzoylCoA thioesterase family active site.
     
 0.907
BF49_2267
Electron transfer flavoproteinubiquinone oxidoreductase EC 1551; Accepts electrons from ETF and reduces ubiquinone.
 
 
 0.867
BF49_0243
2octaprenyl3methyl6methoxy14benzoquinol hydroxylase EC 11413.
  
  
 0.786
ubiG
3demethylubiquinone9 3methyltransferase EC 21164; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 0.786
ubiE
Ubiquinonemenaquinone biosynthesis methyltransferase UbiE EC 211; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
  
 0.767
atpD
ATP synthase beta chain EC 36314; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
   
 0.749
BF49_6911
2octaprenyl6methoxyphenol hydroxylase EC 11413.
  
  
 0.698
BF49_2307
Ubiquinolcytochrome C reductase ironsulfur subunit EC 11022; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
   
 0.690
atpE
ATP synthase F0 sector subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
    
  0.681
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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