Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BF49_3128Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. (553 aa)    
Predicted Functional Partners:
BF49_5173
Acetolactate synthase small subunit EC 2216.
 
 0.936
BF49_2778
Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family.
  
  
 
0.919
ilvC
Ketolacid reductoisomerase EC 11186; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.896
ilvD
Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family.
 
 
 0.830
ilvD-2
Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family.
 
 
 0.812
BF49_1857
Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family.
 
 
 0.772
BF49_0468
Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family.
 
 
 0.755
leuA
2isopropylmalate synthase EC 23313; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.734
BF49_6805
Threonine dehydratase EC 43119.
 
 0.734
BF49_0917
NADdependent malic enzyme EC 11138.
  
 0.693
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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