| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0468 | BF49_2778 | BF49_0468 | BF49_2778 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | 0.663 |
| BF49_0468 | BF49_3128 | BF49_0468 | BF49_3128 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | 0.744 |
| BF49_0468 | BF49_5173 | BF49_0468 | BF49_5173 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Acetolactate synthase small subunit EC 2216. | 0.771 |
| BF49_0468 | BF49_6805 | BF49_0468 | BF49_6805 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Threonine dehydratase EC 43119. | 0.707 |
| BF49_0468 | ilvC | BF49_0468 | BF49_5177 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Ketolacid reductoisomerase EC 11186; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.975 |
| BF49_0468 | leuA | BF49_0468 | BF49_5228 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | 2isopropylmalate synthase EC 23313; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.930 |
| BF49_1857 | BF49_2778 | BF49_1857 | BF49_2778 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | 0.704 |
| BF49_1857 | BF49_3128 | BF49_1857 | BF49_3128 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | 0.762 |
| BF49_1857 | BF49_5173 | BF49_1857 | BF49_5173 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Acetolactate synthase small subunit EC 2216. | 0.803 |
| BF49_1857 | BF49_6805 | BF49_1857 | BF49_6805 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Threonine dehydratase EC 43119. | 0.704 |
| BF49_1857 | ilvC | BF49_1857 | BF49_5177 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | Ketolacid reductoisomerase EC 11186; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.997 |
| BF49_1857 | leuA | BF49_1857 | BF49_5228 | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | 2isopropylmalate synthase EC 23313; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.993 |
| BF49_2778 | BF49_0468 | BF49_2778 | BF49_0468 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | 0.663 |
| BF49_2778 | BF49_1857 | BF49_2778 | BF49_1857 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | 0.704 |
| BF49_2778 | BF49_3128 | BF49_2778 | BF49_3128 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | 0.919 |
| BF49_2778 | BF49_5173 | BF49_2778 | BF49_5173 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Acetolactate synthase small subunit EC 2216. | 0.939 |
| BF49_2778 | BF49_6805 | BF49_2778 | BF49_6805 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Threonine dehydratase EC 43119. | 0.669 |
| BF49_2778 | ilvC | BF49_2778 | BF49_5177 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Ketolacid reductoisomerase EC 11186; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.861 |
| BF49_2778 | ilvD | BF49_2778 | BF49_5541 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | 0.767 |
| BF49_2778 | ilvD-2 | BF49_2778 | BF49_6777 | Benzoylformate decarboxylase EC 4117; Belongs to the TPP enzyme family. | Dihydroxyacid dehydratase EC 4219; Belongs to the IlvD/Edd family. | 0.728 |