STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase protoheme ferrolyase EC 49911; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (344 aa)    
Predicted Functional Partners:
BF49_0208
Protoporphyrinogen IX oxidase novel form HemJ EC 13.
 
  
 0.994
hemE
Uroporphyrinogen III decarboxylase EC 41137; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.936
ctaB
Cytochrome c oxidase polypeptide I EC 1931; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.933
BF49_4968
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
 0.930
BF49_2654
Hypothetical protein.
  
 
 0.894
BF49_6222
InterPro IPR001687IPR002937 COGs COG0492.
  
 
 0.894
BF49_2863
Gll1166 protein.
  
 
 0.793
hemF
Coproporphyrinogen III oxidase aerobic EC 1333; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
   
 0.743
BF49_3179
Bll5199 hypothetical protein.
       0.720
BF49_2404
Porphobilinogen deaminase EC 25161; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.620
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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