Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnhARibonuclease HI EC 31264; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (154 aa)    
Predicted Functional Partners:
dnaQ
DNA polymerase III epsilon subunit EC 2777; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
  
 0.908
BF49_6829
Singlestranded DNAbinding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 
 0.855
thrB
Homoserine kinase EC 27139; Belongs to the pseudomonas-type ThrB family.
       0.853
ispH-2
4hydroxy3methylbut2enyl diphosphate reductase EC 11712; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.806
rnhB
Ribonuclease HII EC 31264; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 0.785
rnhB-2
Ribonuclease HII EC 31264; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 0.785
polA
DNA polymerase I EC 2777; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.756
valS
ValyltRNA synthetase EC 6119; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
   
 
 0.627
BF49_4301
NADPHdependent glyceraldehyde3phosphate dehydrogenase EC 12113 NADdependent glyceraldehyde3phosphate dehydrogenase EC 12112; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.602
thyA
Thymidylate synthase EC 21145; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.599
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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