STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BF49_3441D3phosphoglycerate dehydrogenase EC 11195; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (414 aa)    
Predicted Functional Partners:
BF49_2924
Phosphoserine aminotransferase EC 26152; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
 
 0.996
gpmA
Phosphoglycerate mutase EC 5421; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 0.907
gcvP
Glycine dehydrogenase decarboxylating glycine cleavage system P protein EC 1442; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.635
cysC
Sulfate adenylyltransferase subunit 1 EC 2774 Adenylylsulfate kinase EC 27125; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
  
  
 0.598
BF49_5845
Fumarate hydratase class I aerobic EC 4212; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.575
BF49_3440
Tannase and feruloyl esterase.
       0.553
glyA
Serine hydroxymethyltransferase EC 2121; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.547
BF49_4301
NADPHdependent glyceraldehyde3phosphate dehydrogenase EC 12113 NADdependent glyceraldehyde3phosphate dehydrogenase EC 12112; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.498
BF49_4190
5methyltetrahydrofolatehomocysteine methyltransferase EC 21113; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.497
aroC
Chorismate synthase EC 4235; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.494
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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