| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_3477 | engB | BF49_3477 | BF49_3476 | Hypothetical protein. | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.801 |
| BF49_3477 | yidC | BF49_3477 | BF49_3475 | Hypothetical protein. | Inner membrane protein translocase component YidC long form; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.574 |
| BF49_6148 | engB | BF49_6148 | BF49_3476 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.847 |
| BF49_6148 | era | BF49_6148 | BF49_6517 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPbinding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.722 |
| BF49_6148 | mnmE | BF49_6148 | BF49_0211 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPase and tRNAU34 5formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.808 |
| BF49_6148 | rplM | BF49_6148 | BF49_6600 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L13p L13Ae; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.871 |
| BF49_6148 | rplO | BF49_6148 | BF49_6249 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L15p L27Ae; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.858 |
| BF49_6148 | rplQ | BF49_6148 | BF49_6256 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L17p. | 0.792 |
| BF49_6148 | rplU | BF49_6148 | BF49_0439 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.745 |
| BF49_6148 | rsfS | BF49_6148 | BF49_0427 | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.819 |
| engB | BF49_3477 | BF49_3476 | BF49_3477 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Hypothetical protein. | 0.801 |
| engB | BF49_6148 | BF49_3476 | BF49_6148 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 23S rRNA guanosine2O methyltransferase rlmB EC 211; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.847 |
| engB | era | BF49_3476 | BF49_6517 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | GTPbinding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.796 |
| engB | mnmE | BF49_3476 | BF49_0211 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | GTPase and tRNAU34 5formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.832 |
| engB | rplM | BF49_3476 | BF49_6600 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | LSU ribosomal protein L13p L13Ae; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.801 |
| engB | rplO | BF49_3476 | BF49_6249 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | LSU ribosomal protein L15p L27Ae; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.822 |
| engB | rplQ | BF49_3476 | BF49_6256 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | LSU ribosomal protein L17p. | 0.776 |
| engB | rplU | BF49_3476 | BF49_0439 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.789 |
| engB | rsfS | BF49_3476 | BF49_0427 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.783 |
| engB | yidC | BF49_3476 | BF49_3475 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Inner membrane protein translocase component YidC long form; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.817 |