Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_3869DNA polymerase X family. (560 aa)    
Predicted Functional Partners:
polA
DNA polymerase I EC 2777; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.879
BF49_7325
DNA polymerase III beta subunit EC 2777; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...]
    
 0.841
hisD
Histidinol dehydrogenase EC 11123; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.791
BF49_5678
DglyceroDmannoheptose 17bisphosphate phosphatase EC 311 possible Histidinolphosphatase EC 31315.
    
 0.781
BF49_3749
ATPdependent DNA ligase EC 6511 clustered with Ku protein LigD.
  
 0.753
BF49_3871
ATPdependent DNA ligase EC 6511.
  
 0.753
BF49_4877
ATPdependent DNA ligase EC 6511 clustered with Ku protein LigD.
  
 0.753
hisI
PhosphoribosylAMP cyclohydrolase EC 35419; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
 
 0.651
BF49_0089
ATPdependent DNA ligase EC 6511 LigC.
 
 0.632
BF49_0229
Exodeoxyribonuclease III EC 31112.
   
 0.628
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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