close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_3953HPr kinase. (174 aa)    
Predicted Functional Partners:
BF49_3954
Sensor histidine kinase ChvG EC 273.
 
     0.832
pgl
6phosphogluconolactonase EC 31131 eukaryotic type; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
  
  
 0.789
BF49_3952
PTS system permease IIAMan nitrogen regulatory IIA protein.
 
  
 0.758
BF49_3951
Phosphocarrier protein nitrogen regulation associated.
 
 
 
 0.755
BF49_0310
Prolipoprotein diacylglyceryl transferase EC 2499; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
  
  
 0.694
lgt
Prolipoprotein diacylglyceryl transferase EC 2499; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.694
BF49_3955
DNAbinding response regulator ChvI.
     
 0.565
BF49_0116
PTS IIAlike nitrogenregulatory protein PtsN.
 
  
 0.556
mdh
Malate dehydrogenase EC 11137; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.481
tal
Transaldolase EC 2212 Glucose6phosphate isomerase EC 5319; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
     
 0.475
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: low (22%) [HD]