STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Coexpression
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[Homology]
Score
pyrEOrotate phosphoribosyltransferase EC 24210; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (187 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5phosphate decarboxylase EC 41123; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.999
pyrD
Dihydroorotate dehydrogenase EC 1331; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.999
carB
Carbamoylphosphate synthase large chain EC 6355; Belongs to the CarB family.
 
 
 0.949
pyrB
Aspartate carbamoyltransferase EC 2132; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.936
carA
Carbamoylphosphate synthase small chain EC 6355; Belongs to the CarA family.
 
  
 0.931
BF49_1576
Ribosephosphate pyrophosphokinase EC 2761; Belongs to the ribose-phosphate pyrophosphokinase family.
 
 
 0.908
prs
Ribosephosphate pyrophosphokinase EC 2761; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.897
BF49_4347
Uracil permease.
  
  
 0.880
BF49_6478
Dihydroorotase EC 3523.
 
  
 0.830
phnN
ATPbinding protein PhnN Guanylate kinase EC 2748; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
     
  0.817
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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