Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase EC 1331; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (365 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase EC 24210; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.999
BF49_2231
Dihydroorotase EC 3523.
  
 0.997
BF49_6478
Dihydroorotase EC 3523.
 
 0.997
carB
Carbamoylphosphate synthase large chain EC 6355; Belongs to the CarB family.
 
 0.976
pyrF
Orotidine 5phosphate decarboxylase EC 41123; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.956
carA
Carbamoylphosphate synthase small chain EC 6355; Belongs to the CarA family.
 
  
 0.953
BF49_0651
Dihydroorotase.
     
  0.948
pyrB
Aspartate carbamoyltransferase EC 2132; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.941
guaA
GMP synthase glutaminehydrolyzing EC 6352; Catalyzes the synthesis of GMP from XMP.
 
 0.930
BF49_1337
Dhydantoinase EC 3522.
  
 0.902
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.