STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_4014Cytochrome oxidase biogenesis protein Surf1 facilitates heme A insertion. (250 aa)    
Predicted Functional Partners:
ctaG
Cytochrome oxidase biogenesis protein Cox11CtaG copper delivery to Cox1; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.
 
 
 0.917
ctaA
Heme A synthase cytochrome oxidase biogenesis protein Cox15CtaA; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.
 
 
 0.905
BF49_4013
Conserved hypothetical protein in cyt c oxidase gene clusters.
 
     0.845
BF49_5272
Cytochrome c oxidase polypeptide III EC 1931.
  
 
 0.771
BF49_5273
Cytochrome c oxidase polypeptide I EC 1931; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
  
 
 0.771
ctaB
Cytochrome c oxidase polypeptide I EC 1931; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 
 0.750
BF49_4012
Cytochrome c oxidase polypeptide III EC 1931.
 
  
 0.727
BF49_2306
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 0.717
BF49_0629
Cytochrome O ubiquinol oxidase subunit II EC 1103.
 
 
 0.677
BF49_5274
Cytochrome c oxidase polypeptide II EC 1931.
  
 0.634
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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