STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_4185Threonine dehydratase EC 43119. (315 aa)    
Predicted Functional Partners:
BF49_6765
Threonine synthase EC 4231.
 
 
0.984
BF49_4018
Threonine synthase EC 4231.
  
 
 0.983
BF49_5173
Acetolactate synthase small subunit EC 2216.
  
 
 0.971
BF49_2764
Threonine synthase EC 4231.
 
 
0.967
glyA
Serine hydroxymethyltransferase EC 2121; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.949
trpB
Tryptophan synthase beta chain EC 42120; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.939
BF49_5171
Acetolactate synthase large subunit EC 2216.
 
 0.936
leuB
3isopropylmalate dehydrogenase EC 11185; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.930
BF49_1903
3isopropylmalate dehydrogenase EC 11185.
 
 
 0.929
BF49_5939
Lallothreonine aldolase EC 2121.
  
 
 0.925
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.