| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_1434 | BF49_4253 | BF49_1434 | BF49_4253 | Cobalamin biosynthesis protein CobG. | Sulfate adenylyltransferase subunit 2 EC 2774. | 0.893 |
| BF49_1434 | BF49_4254 | BF49_1434 | BF49_4254 | Cobalamin biosynthesis protein CobG. | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.927 |
| BF49_1434 | BF49_4257 | BF49_1434 | BF49_4257 | Cobalamin biosynthesis protein CobG. | Oxidoreductase probably involved in sulfite reduction. | 0.862 |
| BF49_1434 | BF49_4258 | BF49_1434 | BF49_4258 | Cobalamin biosynthesis protein CobG. | Phosphoadenylylsulfate reductase thioredoxin EC 1848 Adenylylsulfate reductase thioredoxin EC 18410; Reduction of activated sulfate into sulfite. | 0.896 |
| BF49_1434 | BF49_4260 | BF49_1434 | BF49_4260 | Cobalamin biosynthesis protein CobG. | Sulfate transport system permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.775 |
| BF49_1434 | cysA | BF49_1434 | BF49_4262 | Cobalamin biosynthesis protein CobG. | Sulfate and thiosulfate import ATPbinding protein CysA EC 36325; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.835 |
| BF49_1434 | cysC | BF49_1434 | BF49_4252 | Cobalamin biosynthesis protein CobG. | Sulfate adenylyltransferase subunit 1 EC 2774 Adenylylsulfate kinase EC 27125; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. | 0.954 |
| BF49_4253 | BF49_1434 | BF49_4253 | BF49_1434 | Sulfate adenylyltransferase subunit 2 EC 2774. | Cobalamin biosynthesis protein CobG. | 0.893 |
| BF49_4253 | BF49_4254 | BF49_4253 | BF49_4254 | Sulfate adenylyltransferase subunit 2 EC 2774. | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.965 |
| BF49_4253 | BF49_4255 | BF49_4253 | BF49_4255 | Sulfate adenylyltransferase subunit 2 EC 2774. | Conserved hypothetical protein probably involved in sulfate reduction. | 0.648 |
| BF49_4253 | BF49_4256 | BF49_4253 | BF49_4256 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfite reductase NADPH hemoprotein betacomponent EC 1812. | 0.960 |
| BF49_4253 | BF49_4257 | BF49_4253 | BF49_4257 | Sulfate adenylyltransferase subunit 2 EC 2774. | Oxidoreductase probably involved in sulfite reduction. | 0.896 |
| BF49_4253 | BF49_4258 | BF49_4253 | BF49_4258 | Sulfate adenylyltransferase subunit 2 EC 2774. | Phosphoadenylylsulfate reductase thioredoxin EC 1848 Adenylylsulfate reductase thioredoxin EC 18410; Reduction of activated sulfate into sulfite. | 0.997 |
| BF49_4253 | BF49_4260 | BF49_4253 | BF49_4260 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfate transport system permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.992 |
| BF49_4253 | BF49_6922 | BF49_4253 | BF49_6922 | Sulfate adenylyltransferase subunit 2 EC 2774. | Ferredoxinnitrite reductase EC 1771; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.921 |
| BF49_4253 | cysA | BF49_4253 | BF49_4262 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfate and thiosulfate import ATPbinding protein CysA EC 36325; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.992 |
| BF49_4253 | cysC | BF49_4253 | BF49_4252 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfate adenylyltransferase subunit 1 EC 2774 Adenylylsulfate kinase EC 27125; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. | 0.999 |
| BF49_4254 | BF49_1434 | BF49_4254 | BF49_1434 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalamin biosynthesis protein CobG. | 0.927 |
| BF49_4254 | BF49_4253 | BF49_4254 | BF49_4253 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sulfate adenylyltransferase subunit 2 EC 2774. | 0.965 |
| BF49_4254 | BF49_4255 | BF49_4254 | BF49_4255 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Conserved hypothetical protein probably involved in sulfate reduction. | 0.932 |