| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_4253 | BF49_4254 | BF49_4253 | BF49_4254 | Sulfate adenylyltransferase subunit 2 EC 2774. | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.965 |
| BF49_4253 | BF49_4256 | BF49_4253 | BF49_4256 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfite reductase NADPH hemoprotein betacomponent EC 1812. | 0.960 |
| BF49_4253 | BF49_4257 | BF49_4253 | BF49_4257 | Sulfate adenylyltransferase subunit 2 EC 2774. | Oxidoreductase probably involved in sulfite reduction. | 0.896 |
| BF49_4253 | BF49_4258 | BF49_4253 | BF49_4258 | Sulfate adenylyltransferase subunit 2 EC 2774. | Phosphoadenylylsulfate reductase thioredoxin EC 1848 Adenylylsulfate reductase thioredoxin EC 18410; Reduction of activated sulfate into sulfite. | 0.997 |
| BF49_4253 | BF49_4259 | BF49_4253 | BF49_4259 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfate and thiosulfate binding protein CysP. | 0.995 |
| BF49_4253 | BF49_4261 | BF49_4253 | BF49_4261 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfate transport system permease protein CysW. | 0.993 |
| BF49_4253 | BF49_6922 | BF49_4253 | BF49_6922 | Sulfate adenylyltransferase subunit 2 EC 2774. | Ferredoxinnitrite reductase EC 1771; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.921 |
| BF49_4253 | BF49_6923 | BF49_4253 | BF49_6923 | Sulfate adenylyltransferase subunit 2 EC 2774. | Assimilatory nitrate reductase large subunit EC17994. | 0.927 |
| BF49_4253 | cysC | BF49_4253 | BF49_4252 | Sulfate adenylyltransferase subunit 2 EC 2774. | Sulfate adenylyltransferase subunit 1 EC 2774 Adenylylsulfate kinase EC 27125; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. | 0.999 |
| BF49_4253 | cysQ | BF49_4253 | BF49_2745 | Sulfate adenylyltransferase subunit 2 EC 2774. | 325bisphosphate nucleotidase EC 3137; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.969 |
| BF49_4254 | BF49_4253 | BF49_4254 | BF49_4253 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sulfate adenylyltransferase subunit 2 EC 2774. | 0.965 |
| BF49_4254 | BF49_4256 | BF49_4254 | BF49_4256 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sulfite reductase NADPH hemoprotein betacomponent EC 1812. | 0.991 |
| BF49_4254 | BF49_4257 | BF49_4254 | BF49_4257 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Oxidoreductase probably involved in sulfite reduction. | 0.848 |
| BF49_4254 | BF49_4258 | BF49_4254 | BF49_4258 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Phosphoadenylylsulfate reductase thioredoxin EC 1848 Adenylylsulfate reductase thioredoxin EC 18410; Reduction of activated sulfate into sulfite. | 0.989 |
| BF49_4254 | BF49_4259 | BF49_4254 | BF49_4259 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sulfate and thiosulfate binding protein CysP. | 0.763 |
| BF49_4254 | BF49_4261 | BF49_4254 | BF49_4261 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sulfate transport system permease protein CysW. | 0.723 |
| BF49_4254 | BF49_6922 | BF49_4254 | BF49_6922 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Ferredoxinnitrite reductase EC 1771; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.965 |
| BF49_4254 | BF49_6923 | BF49_4254 | BF49_6923 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Assimilatory nitrate reductase large subunit EC17994. | 0.845 |
| BF49_4254 | cysC | BF49_4254 | BF49_4252 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sulfate adenylyltransferase subunit 1 EC 2774 Adenylylsulfate kinase EC 27125; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. | 0.979 |
| BF49_4254 | cysQ | BF49_4254 | BF49_2745 | Siroheme synthase Precorrin2 oxidase EC 13176 Sirohydrochlorin ferrochelatase EC 49914; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 325bisphosphate nucleotidase EC 3137; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.495 |