STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
upp-2Uracil phosphoribosyltransferase EC 2429; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)    
Predicted Functional Partners:
pyrH
Uridine monophosphate kinase EC 27422; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.996
BF49_1194
Cytosine deaminase EC 3541.
  
 
 0.964
BF49_1575
Thymidine phosphorylase EC 2424.
  
 
 0.963
BF49_6761
Cytosine deaminase EC 3541.
   
 0.947
pyrF
Orotidine 5phosphate decarboxylase EC 41123; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.936
surE
5nucleotidase SurE EC 3135; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.911
BF49_2072
5nucleotidase EC 3135; Belongs to the 5'-nucleotidase family.
     
 0.904
BF49_7015
Nucleoside triphosphate pyrophosphohydrolase MazG EC 3618.
    
 0.903
upp
Uracil phosphoribosyltransferase EC 2429; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
  
 
0.902
guaA
GMP synthase glutaminehydrolyzing EC 6352; Catalyzes the synthesis of GMP from XMP.
 
  
 0.890
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.