Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
murDUDPNacetylmuramoylalanineDglutamate ligase EC 6329; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (466 aa)    
Predicted Functional Partners:
murE
UDPNacetylmuramoylalanylDglutamate26 diaminopimelate ligase EC 63213; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
 
 0.999
murC
UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family.
 
 
0.999
murI
Glutamate racemase EC 5113; Provides the (R)-glutamate required for cell wall biosynthesis.
 
  
 0.996
BF49_5049
UDPNacetylmuramoylalanylDglutamyl26 diaminopimelateDalanylDalanine ligase EC 63210.
 
 
 0.988
BF49_5057
DalanineDalanine ligase EC 6324; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.983
mraY
PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
 
 0.982
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 
 0.982
BF49_2984
DalanineDalanine ligase EC 6324; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
 
 0.965
BF49_5047
Cell division protein FtsI Peptidoglycan synthetase EC 241129.
 
  
 0.937
BF49_5053
Cell division protein FtsW; Belongs to the SEDS family.
  
 0.933
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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