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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligADNA ligase EC 6512; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (717 aa)    
Predicted Functional Partners:
BF49_3981
ATPdependent DNA ligase EC 6511 LigC.
    
 0.914
BF49_5106
ATPdependent DNA helicase UvrDPcrA.
 
  
 0.878
BF49_6150
ATPdependent DNA helicase UvrDPcrA proteobacterial paralog.
 
  
 0.847
leuS
LeucyltRNA synthetase EC 6114; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 
 0.821
pheT
PhenylalanyltRNA synthetase beta chain EC 61120; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.746
BF49_0263
16S rRNA m5C 967 methyltransferase EC 211; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.744
BF49_1072
Sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.744
pheS
PhenylalanyltRNA synthetase alpha chain EC 61120; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
  
 0.743
nusB
Transcription termination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
 
  
 0.704
polA
DNA polymerase I EC 2777; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.659
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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