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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase class II EC 4212; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (486 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase EC 11137; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.998
BF49_0338
Succinate dehydrogenase flavoprotein subunit EC 13991; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.995
BF49_0340
Succinate dehydrogenase cytochrome b556 subunit.
  
 
 0.993
BF49_0337
Succinate dehydrogenase ironsulfur protein EC 13991; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.991
BF49_0917
NADdependent malic enzyme EC 11138.
  
 
 0.987
BF49_5845
Fumarate hydratase class I aerobic EC 4212; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.983
BF49_5283
Succinate dehydrogenase ironsulfur protein EC 13991.
  
 0.981
BF49_5196
NADdependent malic enzyme EC 11138.
  
 
 0.978
BF49_1489
Adenylylsulfate reductase alphasubunit EC 18992.
  
 0.972
BF49_2624
Tungstencontaining formate dehydrogenase beta subunit.
  
 0.969
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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