STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hprKHpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (324 aa)    
Predicted Functional Partners:
SEA25061.1
Phosphocarrier protein.
 
 
 
 0.964
SEA25035.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.935
SEA25159.1
PTS system, mannose-specific IIA component.
 
   
 0.885
SEA25249.1
PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.837
SEA25135.1
PTS system, mannose-specific IIB component.
 
   
 0.822
SEA25184.1
UPF0042 nucleotide-binding protein; Displays ATPase and GTPase activities.
     
 0.815
SEA25112.1
PTS system, mannose-specific IIC component.
 
   
 0.790
SEA25087.1
PTS system IID component, Man family.
 
     0.778
SEA56423.1
Phosphonoacetate hydrolase.
 
      0.703
SEA11461.1
PTSINtr with GAF domain, PtsP; Belongs to the PEP-utilizing enzyme family.
 
   
 0.694
Your Current Organism:
Desulfuromusa kysingii
NCBI taxonomy Id: 37625
Other names: D. kysingii, DSM 7343, strain Kysw2
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