node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDZ85148.1 | SEA15946.1 | SAMN05660420_00620 | SAMN05660420_01422 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Cytosine/adenosine deaminase. | 0.701 |
SDZ85148.1 | SEA46791.1 | SAMN05660420_00620 | SAMN05660420_02178 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Sugar or nucleoside kinase, ribokinase family. | 0.607 |
SDZ85148.1 | apt | SAMN05660420_00620 | SAMN05660420_02832 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.917 |
SDZ85148.1 | mtnP | SAMN05660420_00620 | SAMN05660420_02177 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.694 |
SEA11899.1 | mtnA | SAMN05660420_01274 | SAMN05660420_03114 | L-fuculose 1-phosphate aldolase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.968 |
SEA11899.1 | mtnP | SAMN05660420_01274 | SAMN05660420_02177 | L-fuculose 1-phosphate aldolase. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.725 |
SEA15946.1 | SDZ85148.1 | SAMN05660420_01422 | SAMN05660420_00620 | Cytosine/adenosine deaminase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.701 |
SEA15946.1 | SEA52578.1 | SAMN05660420_01422 | SAMN05660420_02317 | Cytosine/adenosine deaminase. | 4Fe-4S binding domain-containing protein. | 0.491 |
SEA15946.1 | apt | SAMN05660420_01422 | SAMN05660420_02832 | Cytosine/adenosine deaminase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.571 |
SEA15946.1 | mtnP | SAMN05660420_01422 | SAMN05660420_02177 | Cytosine/adenosine deaminase. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.682 |
SEA15946.1 | speE | SAMN05660420_01422 | SAMN05660420_00550 | Cytosine/adenosine deaminase. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.539 |
SEA46791.1 | SDZ85148.1 | SAMN05660420_02178 | SAMN05660420_00620 | Sugar or nucleoside kinase, ribokinase family. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.607 |
SEA46791.1 | apt | SAMN05660420_02178 | SAMN05660420_02832 | Sugar or nucleoside kinase, ribokinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.745 |
SEA46791.1 | deoB | SAMN05660420_02178 | SAMN05660420_02412 | Sugar or nucleoside kinase, ribokinase family. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.511 |
SEA46791.1 | mtnP | SAMN05660420_02178 | SAMN05660420_02177 | Sugar or nucleoside kinase, ribokinase family. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.919 |
SEA46791.1 | rlmN | SAMN05660420_02178 | SAMN05660420_02176 | Sugar or nucleoside kinase, ribokinase family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.694 |
SEA52578.1 | SEA15946.1 | SAMN05660420_02317 | SAMN05660420_01422 | 4Fe-4S binding domain-containing protein. | Cytosine/adenosine deaminase. | 0.491 |
SEA52578.1 | mtnP | SAMN05660420_02317 | SAMN05660420_02177 | 4Fe-4S binding domain-containing protein. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.716 |
apt | SDZ85148.1 | SAMN05660420_02832 | SAMN05660420_00620 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.917 |
apt | SEA15946.1 | SAMN05660420_02832 | SAMN05660420_01422 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cytosine/adenosine deaminase. | 0.571 |