STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA47317.1ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily. (1103 aa)    
Predicted Functional Partners:
SEA47297.1
Probable DNA repair protein.
 
 
 0.999
SEA16582.1
Conjugative relaxase domain-containing protein, TrwC/TraI family.
  
 
 0.972
SDZ75713.1
ATP-dependent DNA helicase RecQ.
    
 0.714
recA
Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.609
SEA06988.1
DNA polymerase III, alpha subunit.
  
  
 0.590
ligA
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
  
 
 0.581
SEA77085.1
ATP-dependent DNA helicase PcrA.
 
 
0.579
SDZ96581.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
 
 
0.577
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.554
SEA17118.1
Exonuclease SbcC.
 
  
 0.500
Your Current Organism:
Desulfuromusa kysingii
NCBI taxonomy Id: 37625
Other names: D. kysingii, DSM 7343, strain Kysw2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.