STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA81768.1Aconitase; Belongs to the aconitase/IPM isomerase family. (851 aa)    
Predicted Functional Partners:
SEA06132.1
Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.976
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.964
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.950
SEA46082.1
Zinc-ribbon containing domain-containing protein.
  
 
 0.949
SEA81866.1
Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
 
 
 0.940
SEA35807.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
0.930
SDZ76264.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
 
 0.921
SDZ95602.1
2-oxoglutarate dehydrogenase E1 component.
   
  
 0.895
SEA15250.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.867
SDZ93405.1
Branched-chain amino acid transport system substrate-binding protein.
   
    0.866
Your Current Organism:
Desulfuromusa kysingii
NCBI taxonomy Id: 37625
Other names: D. kysingii, DSM 7343, strain Kysw2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.