node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDI76005.1 | SDI76054.1 | SAMN04487954_101244 | SAMN04487954_101245 | 2,5-diketo-D-gluconate reductase B. | Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.496 |
SDI76005.1 | SDJ48061.1 | SAMN04487954_101244 | SAMN04487954_10547 | 2,5-diketo-D-gluconate reductase B. | S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.740 |
SDI76054.1 | SDI76005.1 | SAMN04487954_101245 | SAMN04487954_101244 | Cytidine and deoxycytidylate deaminase zinc-binding region. | 2,5-diketo-D-gluconate reductase B. | 0.496 |
SDI76054.1 | SDI76099.1 | SAMN04487954_101245 | SAMN04487954_101246 | Cytidine and deoxycytidylate deaminase zinc-binding region. | PadR family transcriptional regulator, regulatory protein AphA. | 0.572 |
SDI76054.1 | SDJ48061.1 | SAMN04487954_101245 | SAMN04487954_10547 | Cytidine and deoxycytidylate deaminase zinc-binding region. | S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.642 |
SDI76054.1 | SDJ83163.1 | SAMN04487954_101245 | SAMN04487954_108141 | Cytidine and deoxycytidylate deaminase zinc-binding region. | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. | 0.472 |
SDI76054.1 | birA | SAMN04487954_101245 | SAMN04487954_11791 | Cytidine and deoxycytidylate deaminase zinc-binding region. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.844 |
SDI76054.1 | hisE | SAMN04487954_101245 | SAMN04487954_103261 | Cytidine and deoxycytidylate deaminase zinc-binding region. | phosphoribosyl-ATP pyrophosphatase. | 0.627 |
SDI76054.1 | ribA-2 | SAMN04487954_101245 | SAMN04487954_11236 | Cytidine and deoxycytidylate deaminase zinc-binding region. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.653 |
SDI76054.1 | ribB | SAMN04487954_101245 | SAMN04487954_11639 | Cytidine and deoxycytidylate deaminase zinc-binding region. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.653 |
SDI76054.1 | thyA | SAMN04487954_101245 | SAMN04487954_11610 | Cytidine and deoxycytidylate deaminase zinc-binding region. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.490 |
SDI76054.1 | upp | SAMN04487954_101245 | SAMN04487954_106140 | Cytidine and deoxycytidylate deaminase zinc-binding region. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.471 |
SDI76099.1 | SDI76054.1 | SAMN04487954_101246 | SAMN04487954_101245 | PadR family transcriptional regulator, regulatory protein AphA. | Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.572 |
SDJ48061.1 | SDI76005.1 | SAMN04487954_10547 | SAMN04487954_101244 | S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 2,5-diketo-D-gluconate reductase B. | 0.740 |
SDJ48061.1 | SDI76054.1 | SAMN04487954_10547 | SAMN04487954_101245 | S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.642 |
SDJ48061.1 | SDJ83163.1 | SAMN04487954_10547 | SAMN04487954_108141 | S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. | 0.457 |
SDJ83163.1 | SDI76054.1 | SAMN04487954_108141 | SAMN04487954_101245 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. | Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.472 |
SDJ83163.1 | SDJ48061.1 | SAMN04487954_108141 | SAMN04487954_10547 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. | S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.457 |
birA | SDI76054.1 | SAMN04487954_11791 | SAMN04487954_101245 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.844 |
birA | ribA-2 | SAMN04487954_11791 | SAMN04487954_11236 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.632 |