STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI94204.1D-serine deaminase, pyridoxal phosphate-dependent. (403 aa)    
Predicted Functional Partners:
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.929
SDK25187.1
Lactoylglutathione lyase.
   
 
  0.927
SDK62424.1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
   
 
  0.927
SDJ48308.1
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
  0.926
SDJ73528.1
Threonine dehydratase.
    
  0.924
SDI81515.1
L-threonine ammonia-lyase.
    
  0.594
SDI94166.1
Enoyl-CoA hydratase.
       0.547
SDI81670.1
Uncharacterized conserved protein.
  
  
  0.492
SDK35216.1
Hypothetical protein.
   
 
  0.462
SDI94130.1
Transcriptional regulator, IclR family.
       0.412
Your Current Organism:
Halomonas gudaonensis
NCBI taxonomy Id: 376427
Other names: CGMCC 1.6133, H. gudaonensis, Halomonas gudaonensis Wang et al. 2007, LMG 23610, LMG:23610, strain SL014B-69
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