STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANF56709.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.998
ANF57476.1
Molybdopterin-synthase adenylyltransferase MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.907
thiC
Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.866
thiE
Thiamine phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.862
ANF57930.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.856
ANF59580.1
Thiamin phosphate synthase superfamily; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.830
ANF56419.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.708
ANF56728.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.708
ttcA
tRNA 2-thiocytidine(32) synthetase TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
  
 
 0.660
tilS
Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 
 0.658
Your Current Organism:
Halotalea alkalilenta
NCBI taxonomy Id: 376489
Other names: CECT 7134, DSM 17697, H. alkalilenta, Halotalea alkalilenta Ntougias et al. 2007, strain AW-7
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